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ESR (Erythrocyte Sedimentation Rate) : An acute phase reactant that measures the rate at which erythrocytes (red blood cells) fall through plasma, a mechanism largely dependent on the plasma concentration of fibrinogen (Shmerling & Greisen, 2025)

Additionally, iodothyronine deiodinases, which are selenium-dependent enzymes, regulate the conversion of T 4 to the biologically active T 3 (Arthur et al., 1992)

2.1 The antagonistic relationship between Th17/Treg during differentiation pathways 2.1.1 Transcription factor regulation A vital mechanism in the control of immunological homeostasis is the mutual antagonistic relationship between RORt and Foxp3 ( Figure 1 ), which is a crucial intrinsic factor affecting the differentiation pathways of Th17 and Treg cells